Another folding problem?

Another View of the Classical Problem of Comparing Two Probabilities

The usual calculation of the P-value for the classical problem of‎ ‎comparing probabilities is not always accurate‎. ‎This‎ ‎issue arose in the context of a legal dispute which depended on when‎ ‎some written material was written in a diary‎. ‎The problem raises‎ ‎some issues on the foundations of statistical inference.‎ 

Folding Problem ( PFP )

The RNA Folding Problem

Because the chemical and biological properties of many RNAs are determined by their conformations, an RNA equivalent exists to the protein folding problem. The RNA folding problem has both a practical side and an academic side. If the practical problem were solved, it would be possible to predict the conformations of RNAs of known sequence. The academic problem has to do with determining what h...

The protein folding problem.

The "protein folding problem" consists of three closely related puzzles: (a) What is the folding code? (b) What is the folding mechanism? (c) Can we predict the native structure of a protein from its amino acid sequence? Once regarded as a grand challenge, protein folding has seen great progress in recent years. Now, foldable proteins and nonbiological polymers are being designed routinely and ...

The Carpenter’s Ruler Folding Problem

A carpenter’s ruler is a ruler divided into pieces of different lengths which are hinged where the pieces meet, which makes it possible to fold the ruler. The carpenter’s ruler folding problem, originally posed by Hopcroft, Joseph and Whitesides, is to determine the smallest case (or interval on the line) into which the ruler fits when folded. The problem is known to be NP-complete. The best pr...